Stem Cell Factor Is a Potent Endothelial Permeability Factor
نویسندگان
چکیده
منابع مشابه
Stem cell factor is a potent endothelial permeability factor.
OBJECTIVE Although stem cell factor (SCF) has been shown to play a critical role in hematopoiesis, gametogenesis, and melanogenesis, the function of SCF in the regulation of vascular integrity has not been studied. APPROACH AND RESULTS We demonstrated that SCF binds to and activates the cKit receptor in endothelial cells, thereby increasing the internalization of vascular endothelial-cadherin...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2014
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.114.303575